CAB39 Antikörper
Kurzübersicht für CAB39 Antikörper (ABIN7239215)
Target
Alle CAB39 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Synthetic peptide of human CAB39
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Isotyp
- IgG
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anti-Calcium Binding Protein 39 (CAB39) (AA 1-341) antibody
CAB39 Reaktivität: Human WB, PLA Wirt: Maus Polyclonal unconjugated
anti-Calcium Binding Protein 39 (CAB39) (AA 28-290) antibodyCAB39 Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Calcium Binding Protein 39 (CAB39) antibodyCAB39 Reaktivität: Human, Maus WB Wirt: Maus Monoclonal 198CT13-9-1 unconjugated
anti-Calcium Binding Protein 39 (CAB39) (C-Term) antibodyCAB39 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Calcium Binding Protein 39 (CAB39) (AA 1-341) antibodyCAB39 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Calcium Binding Protein 39 (CAB39) (C-Term) antibodyCAB39 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Calcium Binding Protein 39 (CAB39) (C-Term) antibodyCAB39 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Fledermaus, Huhn, Affe, Schwein, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
anti-Calcium Binding Protein 39 (CAB39) (Middle Region) antibodyCAB39 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
anti-Calcium Binding Protein 39 (CAB39) (Middle Region) antibodyCAB39 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Saccharomyces cerevisiae WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.7 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- CAB39 (Calcium Binding Protein 39 (CAB39))
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Andere Bezeichnung
- CAB39
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Hintergrund
- Peutz-Jeghers Syndrome (PJS) is a rare hereditary disease characterized by melanocytic macules of the lips, gastrointestinal hamartomatous polyps and an increased risk for many classes of cancer. The serine/threonine kinase LKB1 (also designated STK11) has been identified as the gene mutated in PJS. LKB1 activity increases upon the binding of a regulatory complex consisting of the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase and the calcium binding protein 39 (MO25 alpha). STRAD and MO25 determine the subcellular localization of LKB1 by initiating its translocation from the nucleus to the cytoplasm, thus regulating the tumor suppressor activity of LKB1. The LKB1/STRAD/MO25 complex acts as an AMP-activated protein kinase kinase (AMPKK).
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Molekulargewicht
- 40 kDa
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NCBI Accession
- NP_057373
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UniProt
- Q9Y376
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Pathways
- AMPK Signaling
Target
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