PIM3 Antikörper

Produktnummer ABIN7001376

Produktdetails anti-PIM3 Antikörper

Target: PIM3 (Pim-3 Oncogene (PIM3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIM3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human PIM3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.7 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PIM3

Target: PIM3 (Pim-3 Oncogene (PIM3))

Andere Bezeichnung: PIM3 (PIM3 Produkte)

Synonyme: pim1-a antikoerper, pim-3 antikoerper, BC026639 antikoerper, Kid1 antikoerper, Serine/threonine-protein kinase Pim-3 antikoerper, Pim-3 proto-oncogene, serine/threonine kinase S homeolog antikoerper, Pim-3 proto-oncogene, serine/threonine kinase antikoerper, pim-3 oncogene antikoerper, proviral integration site 3 antikoerper, pim3 antikoerper, pim3.S antikoerper, PIM3 antikoerper, Pim3 antikoerper

Hintergrund: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a selective advantage in tumorigenesis.

NCBI Accession: NP_001001852

UniProt: Q86V86

Pathways: Negative Regulation of Hormone Secretion