CSMD1
Reaktivität: Human
IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
Cy3
Applikationshinweise
IHC 1:50-1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
CSMD1
(CUB and Sushi Multiple Domains 1 (CSMD1))
Andere Bezeichnung
CSMD1
Hintergrund
CSMD1 CUB and Sushi multiple domains 1 is aproteinthat in humans is encoded by theCSMD1gene. It is a potential tumoursuppressor, the deletion of whicHuman, Mouseay result in head and neckcarcinomasbehaving more aggressively. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas.