PFKFB1 Antikörper

Produktnummer ABIN7238606

Produktdetails anti-PFKFB1 Antikörper

Target: PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PFKFB1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human PFKFB1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PFKFB1

Target: PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))

Andere Bezeichnung: PFKFB1 (PFKFB1 Produkte)

Synonyme: zgc:55328 antikoerper, wu:fi11h10 antikoerper, PFKFB1 antikoerper, F6PK antikoerper, HL2K antikoerper, PFRX antikoerper, Pfkfb01 antikoerper, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 antikoerper, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 S homeolog antikoerper, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 antikoerper, pfkfb1 antikoerper, PFKFB1 antikoerper, pfkfb1.S antikoerper, LOC100475853 antikoerper, Pfkfb1 antikoerper

Hintergrund: This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene.

NCBI Accession: NP_002616

UniProt: P16118

Pathways: Regulation of Carbohydrate Metabolic Process