SLC27A1 Antikörper

Produktnummer ABIN7238366

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch SLC27A1 in ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SLC27A1 Antikörper (ABIN7238366)

Target: SLC27A1 (FATP1) (Fatty Acid Transport Protein 1 (FATP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC27A1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-SLC27A1 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human SLC27A1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SLC27A1

Target: SLC27A1 (FATP1) (Fatty Acid Transport Protein 1 (FATP1))

Andere Bezeichnung: SLC27A1

Hintergrund: The protein involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids .Highest levels of expression are detected in muscle and adipose tissue small, intermediate levels in small intestine, and barely detectable in liver.

NCBI Accession: NP_940982

UniProt: Q6PCB7

Pathways: Inositol Metabolic Process, Regulation of Lipid Metabolism by PPARalpha