Der Kaninchen Polyklonal anti-NDUFA12 Antikörper wird verwendet zum Nachweis von NDUFA12 in Proben von Human und Maus. Er wurde validiert für ELISA und IHC.
This gene encodes a protein which is part of mitochondrial complex 1, part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants.