RHOB Antikörper
Kurzübersicht für RHOB Antikörper (ABIN7237824)
Target
Alle RHOB Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Synthetic peptide of human RHOB
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Isotyp
- IgG
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Applikationshinweise
- WB 1:1000-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.4 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- RHOB (Ras Homolog Gene Family, Member B (RHOB))
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Andere Bezeichnung
- RHOB
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Hintergrund
- Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.
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Molekulargewicht
- 22 kDa
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NCBI Accession
- NP_004031
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UniProt
- P62745
Target
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