hras1 antikoerper, MGC78972 antikoerper, MGC132298 antikoerper, RASSF7 antikoerper, C11orf13 antikoerper, HRAS1 antikoerper, HRC1 antikoerper, 2400009B11Rik antikoerper, AW210608 antikoerper, RGD1306244 antikoerper, Ras association domain family member 7 antikoerper, Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 L homeolog antikoerper, Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 antikoerper, RASSF7 antikoerper, rassf7.L antikoerper, rassf7 antikoerper, Rassf7 antikoerper
Hintergrund
RASSF7 (Ras association domain-containing protein 7), also designated HRAS1-related cluster protein 1, is a 373 amino acid protein that localizes to the centrosome. RASSF7, RASSF8, RASSF9 and RASSF10 are four evolutionary conserved proteins that are collectively known as the N-terminal RASSF family. Expressed in skin, neural tube and eye, RASSF7 is believed to play an essential role in mitosis. Further supporting its mitotic role, knockdown of Xenopus RASSF7 has been shown to influence cell failure to form mitotic spindle and also cause nuclear breakdown and apoptosis.