Der Kaninchen Polyklonal anti-HSD17B12 Antikörper (ABIN7237194) detektiert spezifisch HSD17B12 in WB, IHC und ELISA.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.
This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women.