VWA5A Antikörper
Kurzübersicht für VWA5A Antikörper (ABIN7236362)
Target
Alle VWA5A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein of human VWA5A
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Isotyp
- IgG
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anti-Von Willebrand Factor A Domain Containing 5A (VWA5A) (AA 1-786) antibody
VWA5A Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Von Willebrand Factor A Domain Containing 5A (VWA5A) antibodyVWA5A Reaktivität: Human WB, FACS Wirt: Maus Polyclonal unconjugated
anti-Von Willebrand Factor A Domain Containing 5A (VWA5A) (AA 1-415) antibodyVWA5A Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Von Willebrand Factor A Domain Containing 5A (VWA5A) (AA 332-415) antibodyVWA5A Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Von Willebrand Factor A Domain Containing 5A (VWA5A) antibodyVWA5A Reaktivität: Human, Maus, Affe WB, IF, IHC, FACS, IHC (p) Wirt: Maus Monoclonal 3A3 unconjugated
anti-Von Willebrand Factor A Domain Containing 5A (VWA5A) (AA 179-228) antibodyVWA5A Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Von Willebrand Factor A Domain Containing 5A (VWA5A) (C-Term) antibodyVWA5A Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Von Willebrand Factor A Domain Containing 5A (VWA5A) (N-Term) antibodyVWA5A Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Von Willebrand Factor A Domain Containing 5A (VWA5A) (Center) antibodyVWA5A Reaktivität: Human, Maus, Ratte, Affe WB, IF, IC Wirt: Kaninchen Polyclonal unconjugated
anti-Von Willebrand Factor A Domain Containing 5A (VWA5A) (N-Term) antibodyVWA5A Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- IHC 1:100-1:300
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.9 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- VWA5A (Von Willebrand Factor A Domain Containing 5A (VWA5A))
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Andere Bezeichnung
- VWA5A
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Hintergrund
- VWA5A (von Willebrand factor A domain containing 5A), also known as BCSC-1 (breast cancer suppressor candidate 1) or LOH11CR2A (loss of heterozygosity 11 chromosomal region 2 gene A protein), is a 786 amino acid protein containing one VIT domain and one VWFA domain. VWA5A is expressed at low levels in various tissues, with no expression found in 80 % of tumor cell lines. Likely acting as a tumor suppressor gene, deletion of VWA5A leads to loss of heterozygosity (LOH) in breast and ovarian tumors, and may have an important role as a potential gene therapy target. Abnormal expression of VWA5A may lead to an increase in adhesion of CNE-2L2 cells associated with an increase in expression of E-cadherin, alpha-catenin, and p53, resulting in a decrease of malignant activity in cells with ectopic expression of VWA5A.
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UniProt
- O00534
Target
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