Der Kaninchen Polyklonal Anti-RICTOR-Antikörper wurde für ELISA und IHC validiert. Er ist geeignet, RICTOR in Proben von Human und Maus zu detektieren.
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
RICTOR
(RPTOR Independent Companion of mTOR, Complex 2 (RICTOR))
Andere Bezeichnung
RICTOR
Hintergrund
Rapamycin-insensitive companion of mTORis aproteinthat in humans is encoded by theRICTORgene. RICTOR and MTOR are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth. Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors.