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Aggrecan Antikörper (AA 34-147)

Der Kaninchen Polyklonal Anti-Aggrecan-Antikörper wurde für WB, IHC, IP und ICC validiert. Er ist geeignet, Aggrecan in Proben von Maus zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN7434326

Kurzübersicht für Aggrecan Antikörper (AA 34-147) (ABIN7434326)

Target

Alle Aggrecan (ACAN) Antikörper anzeigen
Aggrecan (ACAN)

Reaktivität

  • 91
  • 48
  • 33
  • 19
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Maus

Wirt

  • 90
  • 26
  • 1
  • 1
Kaninchen

Klonalität

  • 83
  • 35
Polyklonal

Konjugat

  • 65
  • 15
  • 7
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Aggrecan Antikörper ist unkonjugiert

Applikation

  • 87
  • 56
  • 38
  • 30
  • 23
  • 14
  • 14
  • 13
  • 8
  • 7
  • 5
  • 4
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 15
    • 9
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 34-147

    Verwendungszweck

    Polyclonal Antibody to Aggrecan (AGC)

    Spezifität

    The antibody is a rabbit polyclonal antibody raised against AGC. It has been selected for its ability to recognize AGC in immunohistochemical staining and western blotting.

    Kreuzreaktivität

    Ratte

    Aufreinigung

    Antigen-specific affinity chromatography followed by Protein A affinity chromatography

    Immunogen

    Recombinant Aggrecan (AGC) corresdonding to Pro34~Glu147 (Accession # Q61282)

    Isotyp

    IgG
  • Applikationshinweise

    Western blotting: 0.01-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

    Kommentare

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.5 mg/mL

    Buffer

    PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

    Haltbarkeit

    24 months
  • Song, Li, Sun, Zhao: "Fxyd5 activates the NF‑κB pathway and is involved in chondrocytes inflammation and extracellular matrix degradation." in: Molecular medicine reports, Vol. 25, Issue 4, (2022) (PubMed).

  • Target

    Aggrecan (ACAN)

    Andere Bezeichnung

    Aggrecan

    Hintergrund

    ACAN, AGC1, AGCAN, CSPG1, CSPCP, CSPGCP, MSK16, SEDK, Cartilage-specific proteoglycan core protein, Large Aggregating Proteoglycan, Chondroitin Sulfate Proteoglycan 1

    UniProt

    Q61282

    Pathways

    Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
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