SARS-CoV-2 ORF7a Antikörper

Produktnummer ABIN6992306

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SARS-CoV-2 ORF7a in ELISA und IHC. Er zeigt eine Reaktivität gegenüber SARS Coronavirus-2 (SARS-CoV-2).

Kurzübersicht für SARS-CoV-2 ORF7a Antikörper (ABIN6992306)

Target: SARS-CoV-2 ORF7a

Reaktivität: SARS Coronavirus-2 (SARS-CoV-2)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SARS-CoV-2 ORF7a Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-SARS-CoV-2 ORF7a Antikörper

Aufreinigung: SARS-CoV-2 (COVID-19) ORF7a Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-SARS-CoV-2 (COVID-19) ORF7a antibody was raised against a peptide corresponding to 15 amino acids near the central domain of SARS-CoV-2 (COVID-19) ORF7a protein. The immunogen is located within 40-90 amino acids of the SARS-CoV-2 (COVID-19) ORF7a protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC: 1 μ,g/mL Antibody validated: Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) ORF7a antibody can detect 2 ng of free peptide at 1 μ,g/mL in ELISA. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SARS-CoV-2 (COVID-19) ORF7a antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SARS-CoV-2 (COVID-19) ORF7a antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SARS-CoV-2 ORF7a

Target: SARS-CoV-2 ORF7a

Substanzklasse: Viral Protein

Hintergrund: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). SARS-CoV-2 virus proteins include structural proteins, non-structural proteins and accessory factors. The structure of SARS-CoV-2 consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. SARS-CoV-2 non-structural protein is ORF1ab that consists of 16 proteins (nsp1-nsp16), while accessory factors include ORF3a, ORF3b, ORF6, ORF7a, ORF7b, ORF8, ORF9b, ORF7a and ORF7a. ORF7a plays a role as antagonist of host tetherin (BST2), disrupting its antiviral effect. It acts by binding to BST2 thereby interfering with its glycosylation. It may suppress small interfering RNA (siRNA) and may bind to host ITGAL, thereby playing a role in attachment or modulation of leukocytes (3).

Molekulargewicht: 14kD kDa

Gen-ID: 43740573

UniProt: P0DTC7