SARS-CoV-2 NSP16 Antikörper (AA 120-170)
Kurzübersicht für SARS-CoV-2 NSP16 Antikörper (AA 120-170) (ABIN6992287)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 120-170
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Aufreinigung
- SARS-CoV-2 (COVID-19) NSP16 Antibody is affinity chromatography purified via peptide column.
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Immunogen
- Anti-SARS-CoV-2 (COVID-19) NSP16 antibody was raised against a peptide corresponding to 16 amino acids near the central domain of SARS-CoV-2 (COVID-19) NSP16 protein. The immunogen is located within 120-170 amino acids of the SARS-CoV-2 (COVID-19) NSP16 protein.
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Isotyp
- IgG
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Applikationshinweise
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IHC: 0.5 μ,g/mL, WB: 0.5 μ,g/mL
Antibody validated: Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) NSP16 antibody can detect 2 ng of free peptide at 1 μ,g/mL in ELISA. It can detect SARS-CoV-2 NSP16 recombinant protein by ELISA and WB. All other applications and species not yet tested. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- SARS-CoV-2 (COVID-19) NSP16 antibody is supplied in PBS containing 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,4 °C
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Informationen zur Lagerung
- SARS-CoV-2 (COVID-19) NSP16 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SARS-CoV-2 NSP16 (SARS-CoV-2 2'-O-Ribose Methyltransferase (SARS-CoV-2 NSP16))
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Andere Bezeichnung
- SARS-CoV-2 NSP16
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Substanzklasse
- Viral Protein
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Hintergrund
- Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Methyltransferase mediates mRNA cap 2'-O-ribose methylation to the 5'-cap structure of viral mRNAs. N7-methyl guanosine cap is a prerequisite for binding of nsp16. Therefore plays an essential role in viral mRNAs cap methylation which is essential to evade immune system.
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Gen-ID
- 43740578
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NCBI Accession
- YP_009725311
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UniProt
- P0DTC1
Target
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