SARS-CoV-2 NSP12 (RdRP) Antikörper (C-Term)

Produktnummer ABIN6992285

Produktdetails anti-SARS-CoV-2 NSP12 (RdRP) Antikörper

Target: SARS-CoV-2 NSP12 (RdRP) (SARS-CoV-2 RdRP) (SARS-CoV-2 RNA-dependent RNA Polymerase (NSP12) (SARS-CoV-2 RdRP))

Bindungsspezifität: C-Term

Reaktivität: SARS Coronavirus-2 (SARS-CoV-2)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SARS-CoV-2 NSP12 (RdRP) Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: SARS-CoV-2 (COVID-19) NSP12 antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-SARS-CoV-2 (COVID-19) NSP12 antibody was raised against a peptide corresponding to 16 amino acids near the carboxyl terminus of SARS-CoV-2 (COVID-19) NSP12 protein. The immunogen is located within the last 50 amino acids of the SARS-CoV-2 (COVID-19) NSP12 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1-2 μ,g/mL

Antibody validated: SARS-CoV-2 (COVID-19) NSP12 antibody can detect 2 ng of free peptide at 1 ?g/mL in ELISA. It can detect SARS-CoV-2 NSP12 recombinant protein by ELISA and WB. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SARS-CoV-2 (COVID-19) NSP12 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SARS-CoV-2 (COVID-19) NSP12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Referenzen für anti-SARS-CoV-2 NSP12 (RdRP) Antikörper (ABIN6992285)

Sun, Abriola, Niederer, Pedersen, Alfajaro, Silva Monteiro, Wilen, Ho, Gilbert, Surovtseva, Lindenbach, Guo: "Restriction of SARS-CoV-2 replication by targeting programmed -1 ribosomal frameshifting." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, Issue 26, (2021) (PubMed).

Details zu SARS-CoV-2 NSP12 (RdRP)

Target: SARS-CoV-2 NSP12 (RdRP) (SARS-CoV-2 RdRP) (SARS-CoV-2 RNA-dependent RNA Polymerase (NSP12) (SARS-CoV-2 RdRP))

Andere Bezeichnung: SARS-CoV-2 NSP12 (SARS-CoV-2 RdRP Produkte)

Synonyme: pp1ab antikoerper, ORF1a polyprotein;ORF1ab polyprotein antikoerper, ORF1ab antikoerper

Substanzklasse: Viral Protein

Hintergrund: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP12 interacts with nsp7 and nsp8.

Gen-ID: 43740578

UniProt: P0DTC1