PDCD1LG2 Antikörper (Extracellular Domain)

Produktnummer ABIN6992229

Dieses Anti-PDCD1LG2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von PDCD1LG2 in WB, FACS, ELISA, ICC, IF und IHC (p). Geeignet für Human.

Kurzübersicht für PDCD1LG2 Antikörper (Extracellular Domain) (ABIN6992229)

Target: PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PDCD1LG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 7C1

Produktdetails anti-PDCD1LG2 Antikörper

Bindungsspezifität: Extracellular Domain

Aufreinigung: PD-L2 Antibody is supplied as protein A purified IgG2b.

Immunogen: PD-L2 antibody was raised against the extracellular domain of human PD-L2.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: PD-L2 antibody can be used for detection of PD-L2 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples, Immunocytochemistry in human samples, Immunofluorescence in human samples and Flow Cytometry in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PD-L2 Antibody is supplied in PBS containing 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PD-L2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PDCD1LG2

Target: PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

Andere Bezeichnung: PDL2

Hintergrund: PD-L2 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PD-L2 can act to stimulate an immunogenic response through and alternative receptor from PD-1.

Molekulargewicht: Predicted: 30 kDa

Observed: 38 kDa

Gen-ID: 80380

NCBI Accession: NP_079515

UniProt: P9BQ51