MLXIP Antikörper (N-Term)

Produktnummer ABIN6992189

Der Kaninchen Polyklonal Anti-MLXIP-Antikörper wurde für ELISA und WB validiert. Er ist geeignet, MLXIP in Proben von Human zu detektieren.

Kurzübersicht für MLXIP Antikörper (N-Term) (ABIN6992189)

Target: MLXIP (MLX Interacting Protein (MLXIP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MLXIP Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-MLXIP Antikörper

Bindungsspezifität: N-Term

Aufreinigung: MLXIP Antibody is affinity chromatography purified via peptide column.

Immunogen: MLXIP antibody was raised against a peptide corresponding to 19 amino acids near the amino terminus of human MLXIP.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: MLXIP antibody can be used for Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: MLXIP Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: MLXIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu MLXIP

Target: MLXIP (MLX Interacting Protein (MLXIP))

Andere Bezeichnung: MLXIP

Hintergrund: MLXIP Antibody: MLXIP is a member of the Myc superfamily of transcription factors and functions as part of a heterodimer with Max-like protein X (MLX) to activate transcription (1). MLXIP contributes to the regulation of glucose homeostasis as the MLXIP/MLX heterodimer activates expression of thioredoxin-interacting protein (TXNIP), a potent inhibitor of cellular glucose uptake and aerobic glycolysis. The mammalian target of rapamycin (mTOR) suppresses the activation of the TXNIP pathway by binding to MLXIP, thereby preventing the MLXIP/MLX heterodimer formation (2). MLXIP interaction with Myc may also be involved in metabolic reprogramming and tumorigenesis (3).

Molekulargewicht: Predicted: 20 kDa

Observed: 21 kDa

Gen-ID: 22877

NCBI Accession: NP_055753

UniProt: Q9HAP2