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TRIM58 Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TRIM58 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN6992188

Kurzübersicht für TRIM58 Antikörper (C-Term) (ABIN6992188)

Target

TRIM58 (Tripartite Motif Containing 58 (TRIM58))

Reaktivität

  • 11
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 9
  • 2
Kaninchen

Klonalität

  • 10
  • 1
Polyklonal

Konjugat

  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TRIM58 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 7
    • 2
    • 2
    • 1
    C-Term

    Aufreinigung

    TRIM58 Antibody is affinity chromatography purified via peptide column.

    Immunogen

    TRIM58 antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human TRIM58.

    Isotyp

    IgG
  • Applikationshinweise

    TRIM58 antibody can be used for Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human and mouse samples. All other applications and species not yet tested.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    TRIM58 Antibody is supplied in PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,4 °C

    Informationen zur Lagerung

    TRIM58 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target

    TRIM58 (Tripartite Motif Containing 58 (TRIM58))

    Andere Bezeichnung

    TRIM58

    Hintergrund

    TRIM58 Antibody: TRIM58 is a member of the tripartite motif-containing family of proteins that frequently possess E3 ubiquitin ligase activities (1). TRIM58 is strongly expressed in erythroid lineage cells and is further upregulated during late erythroid maturation. Recent experiments suggest that TRIM58 facilitates erythroblast enucleation by ubiquitinating the intermediate chain of the microtubule motor dynein, thereby inducing proteolytic degradation (2).

    Molekulargewicht

    Predicted: 53 kDa

    Observed: 56 kDa

    Gen-ID

    25893

    NCBI Accession

    NP_056246

    UniProt

    Q8NG06
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