TRIM58 Antikörper (C-Term)

Produktnummer ABIN6992188

Produktdetails anti-TRIM58 Antikörper

Target: TRIM58 (Tripartite Motif Containing 58 (TRIM58))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM58 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: TRIM58 Antibody is affinity chromatography purified via peptide column.

Immunogen: TRIM58 antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human TRIM58.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TRIM58 antibody can be used for Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human and mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TRIM58 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TRIM58 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TRIM58

Target: TRIM58 (Tripartite Motif Containing 58 (TRIM58))

Andere Bezeichnung: TRIM58 (TRIM58 Produkte)

Hintergrund: TRIM58 Antibody: TRIM58 is a member of the tripartite motif-containing family of proteins that frequently possess E3 ubiquitin ligase activities (1). TRIM58 is strongly expressed in erythroid lineage cells and is further upregulated during late erythroid maturation. Recent experiments suggest that TRIM58 facilitates erythroblast enucleation by ubiquitinating the intermediate chain of the microtubule motor dynein, thereby inducing proteolytic degradation (2).

Molekulargewicht: Predicted: 53 kDa

Observed: 56 kDa

Gen-ID: 25893

NCBI Accession: NP_056246

UniProt: Q8NG06