SUSD3 Antikörper (AA 120-170)

Produktnummer ABIN6992182

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SUSD3 in ELISA, WB und ICC. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für SUSD3 Antikörper (AA 120-170) (ABIN6992182)

Target: SUSD3 (Sushi Domain Containing 3 (SUSD3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUSD3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunocytochemistry (ICC)

Produktdetails anti-SUSD3 Antikörper

Bindungsspezifität: AA 120-170

Spezifität: SUSD3 antibody is human and mouse reactive. Multiple isoforms of SUSD3 are known to exist.

Aufreinigung: SUSD3 Antibody is affinity chromatography purified via peptide column.

Immunogen: SUSD3 antibody was raised against a 16 amino acid peptide from near the center of human SUSD3. The immunogen is located within amino acids 120 - 170 of SUSD3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SUSD3 antibody can be used for the detection of SUSD3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SUSD3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SUSD3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu SUSD3

Target: SUSD3 (Sushi Domain Containing 3 (SUSD3))

Andere Bezeichnung: SUSD3

Hintergrund: Little is known of the function of the sushi domain containing 3 protein (SUSD3), but its expression has been reported in estrogen receptor-alpha (ERalpha)-positive breast tumors with decreased expression reported in aggressive malignant tumors (1,2). Recently, SUSD3 has been found to promote estrogen-dependent cell proliferation and may regulate cell-cell and cell-substrate interactions and migration in breast cancer (3). Furthermore, elevated SUSD3 mRNA levels were observed in aromatase inhibitor-responsive breast tumors, suggesting that it may also serve as a novel predictor of response to endocrine therapy and a potential therapeutic target (3).

Molekulargewicht: Predicted: 16, 22, 23, 28 kDa

Observed: 23 kDa

Gen-ID: 203328

NCBI Accession: NP_659443

UniProt: Q96L08