SRPK1 Antikörper (N-Term)

Produktnummer ABIN6992178

Dieses Anti-SRPK1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SRPK1 in WB, ELISA und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für SRPK1 Antikörper (N-Term) (ABIN6992178)

Target: SRPK1 (SRSF Protein Kinase 1 (SRPK1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRPK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SRPK1 Antikörper

Bindungsspezifität: N-Term

Spezifität: SRPK1 antibody is human, mouse and rat reactive. Multiple isoforms of SRPK1 are known to exist, this antibody will detect all except isoforms b and e. SRPK1 antibody is predicted to not cross-react with SRPK2.

Aufreinigung: SRPK1 Antibody is affinity chromatography purified via peptide column.

Immunogen: SRPK1 antibody was raised against a 19 amino acid peptide from near the amino terminus of human SRPK1. The immunogen is located within the first 50 amino acids of SRPK1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SRPK1 antibody can be used for the detection of SRPK1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SRPK1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SRPK1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu SRPK1

Target: SRPK1 (SRSF Protein Kinase 1 (SRPK1))

Andere Bezeichnung: SRPK1

Hintergrund: SRPK1 and SRPK2, two Arginine/serine-rich (SR) protein-specific kinases constitute control circuits to regulate both constitutive and alternative pre-mRNA splicing and coordinate splicing with transcription in cells (1). They are highly specific for the phosphorylation of these RS proteins, and highly expressed in testis (1,2). SRPK1 plays a role in the condensation of sperm chromatin and controls the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis (3,4).

Molekulargewicht: Predicted: 54, 72, 91 kDa

Observed: 91 kDa

Gen-ID: 6732

NCBI Accession: NP_003128

UniProt: Q96SB4

Pathways: Toll-Like Receptors Cascades