PALMD Antikörper (C-Term)

Produktnummer ABIN6992156

Der Kaninchen Polyklonal anti-PALMD Antikörper wird verwendet zum Nachweis von PALMD in Proben von Human. Er wurde validiert für WB, ELISA und IHC (p).

Kurzübersicht für PALMD Antikörper (C-Term) (ABIN6992156)

Target: PALMD (Palmdelphin (PALMD))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PALMD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PALMD Antikörper

Bindungsspezifität: AA 460-510, C-Term

Spezifität: PALMD antibody is human specific. At least two isoforms are known to exist.

Aufreinigung: PALMD antibody is affinity chromatography purified via peptide column.

Immunogen: PALMD antibody was raised against a 15 amino acid peptide near the carboxy terminus of human PALMD. The immunogen is located within amino acids 460 - 510 of PALMD.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PALMD antibody can be used for detection of PALMD by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PALMD antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PALMD antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu PALMD

Target: PALMD (Palmdelphin (PALMD))

Andere Bezeichnung: PALMD

Hintergrund: Palmdelphin (PALMD) is a member of the paralemmin families that are lipid-anchored proteins having a role in the cell shape control and cell dynamics (1,2). While Paralemmin proteins typically anchor to the cytoplasm through via palmytoylation and prenylation, PALMD is found predominantly in the cytosol (3). PALMD is targeted to the nucleus to induce apoptosis in response to DNA damage (3-5). Abnormal genetic alterations in PALMD are observed in many malignant tumors (5).

Molekulargewicht: Predicted: 61 kDa

Observed: 60 kDa

Gen-ID: 54873

NCBI Accession: NP_060204

UniProt: Q9NP74