S1PR2 Antikörper (C-Term)

Produktnummer ABIN6992153

Der Kaninchen Polyklonal Anti-S1PR2-Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, S1PR2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für S1PR2 Antikörper (C-Term) (ABIN6992153)

Target: S1PR2 (Sphingosine-1-Phosphate Receptor 2 (S1PR2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser S1PR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-S1PR2 Antikörper

Bindungsspezifität: AA 270-320, C-Term

Spezifität: S1PR2 antibody is human, mouse and rat reactive.

Aufreinigung: S1PR2 antibody is affinity chromatography purified via peptide column.

Immunogen: S1PR2 antibody was raised against an 16 amino acid peptide near the carboxy terminus of human S1PR2. The immunogen is located within amino acids 270 - 320 of S1PR2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: S1PR2 antibody can be used for detection of S1PR2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry at 10 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: S1PR2 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: S1PR2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu S1PR2

Target: S1PR2 (Sphingosine-1-Phosphate Receptor 2 (S1PR2))

Andere Bezeichnung: S1PR2

Hintergrund: The Sphingosine 1-phosphate receptor 2 (S1PR2) protein was initially identified as G-protein coupled receptor thought to be involved in development (1) and was found to mediate sphingosine 1-phosphate (SPP)-induced cell rounding and neurite retraction (2). S1PR2 and the related protein S1PR3 (also known as EDG3) are also thought to mediate the SPP-induced cell proliferation, survival, and related signaling events (3). S1PR2 has also been found to be key regulator in acute vascular inflammation and may be a novel therapeutic target for vascular disorders (4).

Molekulargewicht: Predicted: 39 kDa

Observed: 50 kDa

Gen-ID: 9294

NCBI Accession: NP_004221

UniProt: O95136

Pathways: Synaptic Membrane