MAGEA4 Antikörper (N-Term)

Produktnummer ABIN6992141

Der Kaninchen Polyklonal Anti-MAGEA4-Antikörper wurde für WB, ELISA, IHC (p) und IF validiert. Er ist geeignet, MAGEA4 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für MAGEA4 Antikörper (N-Term) (ABIN6992141)

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAGEA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-MAGEA4 Antikörper

Bindungsspezifität: N-Term

Spezifität: MAGEA4 antibody is human specific. At least four isoforms of MAGEA4 are known to exist.

Aufreinigung: MAGEA4 antibody is affinity chromatography purified via peptide column.

Immunogen: MAGEA4 antibody was raised against a 16 amino acid peptide near the amino terminus of human MAGEA4. The immunogen is located within the first 50 amino acids of MAGEA4.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: MAGEA4 antibody can be used for detection of MAGEA4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: MAGEA4 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: MAGEA4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu MAGEA4

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Andere Bezeichnung: MAGEA4

Hintergrund: MAGEA4 is a member of the melanoma-associated antigen family that consists of a number of antigens recognized by cytotoxic T lymphocytes (1). MAGEA4 may serve as a target for antitumoral vaccination and may play a role in embryonal development and tumor transformation or aspects of tumor progression. It is expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma and have been implicated in some hereditary disorders, such as dyskeratosis congenital (2-4).

Molekulargewicht: Predicted: 35 kDa

Observed: 45 kDa

Gen-ID: 4103

NCBI Accession: NP_001011550

UniProt: P43358