QSOX1 Antikörper (AA 360-410)

Produktnummer ABIN6992133

Der Kaninchen Polyklonal anti-QSOX1 Antikörper (ABIN6992133) detektiert spezifisch QSOX1 in WB, ELISA, IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für QSOX1 Antikörper (AA 360-410) (ABIN6992133)

Target: QSOX1 (Quiescin Q6 Sulfhydryl Oxidase 1 (QSOX1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser QSOX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-QSOX1 Antikörper

Bindungsspezifität: AA 360-410

Spezifität: QSOX1 antibody is human and mouse reactive. QSOX1 antibody is predicted to not cross-react with QSOX2.

Aufreinigung: QSOX1 antibody is affinity chromatography purified via peptide column.

Immunogen: QSOX1 antibody was raised against a 17 amino acid peptide near the center of human QSOX1. The immunogen is located within amino acids 360 - 410 of QSOX1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: QSOX1 antibody can be used for detection of QSOX1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: QSOX1 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: QSOX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu QSOX1

Target: QSOX1 (Quiescin Q6 Sulfhydryl Oxidase 1 (QSOX1))

Andere Bezeichnung: QSOX1

Hintergrund: The QSOX1 gene, also known as Quiescin Q6, is a fusion of two ancient genes: thioredoxin and ERV1. Its expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation (1). The QSOX1 protein oxidizes sulfhydryl groups to form disulfide bonds in proteins. QSOX1 expression is induced by hypoxia (2) and appears to protect cells against oxidative stress-induced apoptosis (3).

Molekulargewicht: Predicted: 65, 82 kDa

Observed: 66 kDa

Gen-ID: 5768

NCBI Accession: NP_002817

UniProt: O00391

Pathways: Cell RedoxHomeostasis