SLC29A3 Antikörper (N-Term)

Produktnummer ABIN6992117

Der Kaninchen Polyklonal anti-SLC29A3 Antikörper wird verwendet zum Nachweis von SLC29A3 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, ELISA, IHC (p) und IF.

Kurzübersicht für SLC29A3 Antikörper (N-Term) (ABIN6992117)

Target: SLC29A3 (Solute Carrier Family 29 Member 3 (SLC29A3))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC29A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-SLC29A3 Antikörper

Bindungsspezifität: N-Term

Spezifität: SLC29A3 antibody is human, mouse and rat reactive. At least two isoforms of SLC29A3 are known to exist, this antibody will detect both isoforms. SLC29A3 antibody is predicted to not cross-react with other SLC29 proteins.

Aufreinigung: SLC29A3 antibody is affinity chromatography purified via peptide column.

Immunogen: SLC29A3 antibody was raised against a 19 amino acid peptide near the amino terminus of human SLC29A3. The immunogen is located within the first 50 amino acids of SLC29A3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SLC29A3 antibody can be used for detection of SLC29A3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SLC29A3 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SLC29A3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu SLC29A3

Target: SLC29A3 (Solute Carrier Family 29 Member 3 (SLC29A3))

Andere Bezeichnung: SLC29A3

Hintergrund: SLC29A3 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1,2). SLC29A3 is a transmembrane glycoprotein that localizes to the lysosomal membrane and is a broad selectivity, low affinity nucleoside transporter (3). Mutations in the SLC29A3 gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism (4). A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus (5).

Molekulargewicht: Predicted: 52 kDa

Observed: 51 kDa

Gen-ID: 55315

NCBI Accession: NP_060814

UniProt: Q9BZD2