Ectodysplasin A Antikörper (AA 130-180)

Produktnummer ABIN6992088

Dieses Anti-Ectodysplasin A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Ectodysplasin A in WB, ELISA, IHC (p) und IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Ectodysplasin A Antikörper (AA 130-180) (ABIN6992088)

Target: Ectodysplasin A (EDA)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ectodysplasin A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-Ectodysplasin A Antikörper

Bindungsspezifität: AA 130-180

Spezifität: EDA1 antibody is human, mouse and rat reactive. Multiple isoforms of EDA1 are known to exist.

Aufreinigung: EDA1 antibody is affinity chromatography purified via peptide column.

Immunogen: EDA1 antibody was raised against an 19 amino acid peptide near the center of human EDA1. The immunogen is located within amino acids 130 - 180 of EDA1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: EDA1 antibody can be used for detection of EDA1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: EDA1 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: EDA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu Ectodysplasin A

Target: Ectodysplasin A (EDA)

Andere Bezeichnung: EDA1

Hintergrund: Ectodysplasin A (EDA1) is a member of the TNF-related ligand family involved in the early epithelial-mesenchymal interaction that regulates ectodermal appendage formation (1). It is a trimeric type II membrane protein that co-localizes with cytoskeletal structures at the lateral and apical surfaces of cells and can be expressed as eight alternatively spliced isoforms in hair follicles and in the epidermis of adult skin (2,3). EDAs are required during development, and loss or mutation of EDA1 results in a group of developmental disorders identified as ectodermal dysplasia type 1 (4,5).

Molekulargewicht: Predicted: 16, 43 kDa

Observed: 39 kDa

Gen-ID: 1896

NCBI Accession: NP_001390

UniProt: Q92838

Pathways: Tube Formation