KLF17 Antikörper (C-Term)

Produktnummer ABIN6992086

Produktdetails anti-KLF17 Antikörper

Target: KLF17 (Kruppel-Like Factor 17 (KLF17))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLF17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: KLF17 antibody is human, mouse and rat reactive. At least two isoforms of KLF17 are known to exist, this antibody will only detect the large isoform. KLF17 antibody is predicted to not cross-react with other KLF proteins.

Aufreinigung: KLF17 antibody is affinity chromatography purified via peptide column.

Immunogen: KLF17 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human KLF17. The immunogen is located within the last 50 amino acids of KLF17.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: KLF17 antibody can be used for detection of KLF17 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: KLF17 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: KLF17 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu KLF17

Target: KLF17 (Kruppel-Like Factor 17 (KLF17))

Andere Bezeichnung: KLF17 (KLF17 Produkte)

Synonyme: zfp393 antikoerper, znf393 antikoerper, neptune antikoerper, rp4-675g8.1 antikoerper, ZNF393 antikoerper, Zfp393 antikoerper, 7420700M05Rik antikoerper, AA420409 antikoerper, AU043468 antikoerper, C85123 antikoerper, D4Ertd561e antikoerper, Gzf antikoerper, Kruppel-like factor 17 L homeolog antikoerper, Kruppel like factor 17 antikoerper, Kruppel-like factor 17 antikoerper, klf17.L antikoerper, KLF17 antikoerper, klf17 antikoerper, Klf17 antikoerper

Hintergrund: KLF17, also known as ZNF393, is a member of the Sp/KLF family of transcription factors (1,2). KLF17 binds to the promoter and negatively regulates the transcription of Id-1, a key metastasis regulator in breast cancer (3). Suppression of KLF17 promotes breast cancer cell invasion and epithelial-mesenchymal transition (3). Down-regulated KLF17 expression is also associated tumor invasion and poor prognosis in hepatocellular carcinoma, suggesting that the level of KLF17 expression can serve as a prognostic indicator (4).

Molekulargewicht: Predicted: 28, 39, 43 kDa

Observed: 38 kDa

Gen-ID: 128209

NCBI Accession: NP_775755

UniProt: Q5JT82