NOSTRIN Antikörper (C-Term)

Produktnummer ABIN6992085

Produktdetails anti-NOSTRIN Antikörper

Target: NOSTRIN (Nitric Oxide Synthase Trafficker (NOSTRIN))

Bindungsspezifität: AA 430-480, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOSTRIN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: NOSTRIN antibody is human, mouse and rat reactive. At least four isoforms are known to exist, this antibody will detect all four isoforms.

Aufreinigung: NOSTRIN antibody is affinity chromatography purified via peptide column.

Immunogen: NOSTRIN antibody was raised against a 17 amino acid peptide near the carboxy terminus of human NOSTRIN. The immunogen is located within amino acids 430 - 480 of NOSTRIN.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: NOSTRIN antibody can be used for detection of NOSTRIN by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: NOSTRIN antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: NOSTRIN antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu NOSTRIN

Target: NOSTRIN (Nitric Oxide Synthase Trafficker (NOSTRIN))

Andere Bezeichnung: NOSTRIN (NOSTRIN Produkte)

Synonyme: NOSTRIN antikoerper, MGC171848 antikoerper, Daip2 antikoerper, mDaIP2 antikoerper, DaIP2 antikoerper, nitric oxide synthase trafficking antikoerper, nitric oxide synthase trafficking L homeolog antikoerper, nitric oxide synthase trafficker antikoerper, NOSTRIN antikoerper, nostrin antikoerper, nostrin.L antikoerper, Nostrin antikoerper

Hintergrund: NOSTRIN. also known as endothelial nitric oxide synthase traffic inducer, is a member of the Pombe Cdc15 homology (PCH) family of proteins which may function as the modulator of the subcellular localisation and activity of endothelial nitric oxide synthase (eNOS) (1,2). It decreases NOS3 activity by inducing its translocation away from the plasma membrane (3). NOSTRIN typically exists as a trimer and is expressed in the vascular endothelial cells of highly vascularized tissues such as placenta, lung, kidney and heart. NOSTRIN is necessary for proper vascular development in zebrafish and postnatal retinal angiogenesis in mice (4,5).

Molekulargewicht: Predicted: 47, 53, 56, 62 kDa

Observed: 68 kDa

Gen-ID: 115677

NCBI Accession: NP_443178

UniProt: Q8IVI9