CADM3 Antikörper (AA 220-270)

Produktnummer ABIN6992066

Produktdetails anti-CADM3 Antikörper

Target: CADM3 (Cell Adhesion Molecule 3 (CADM3))

Bindungsspezifität: AA 220-270

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CADM3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: CADM3 antibody is human, mouse and rat reactive. At least three isoforms are known to exist, this antibody will only detect the two longest isoforms. CADM3 antibody is predicted to not cross-react with other members of the CADM protein family.

Aufreinigung: CADM3 antibody is affinity chromatography purified via peptide column.

Immunogen: CADM3 antibody was raised against a 16 amino acid peptide near the center of human CADM3. The immunogen is located within amino acids 220 - 270 of CADM3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CADM3 antibody can be used for detection of CADM3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: CADM3 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: CADM3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu CADM3

Target: CADM3 (Cell Adhesion Molecule 3 (CADM3))

Andere Bezeichnung: CADM3 (CADM3 Produkte)

Synonyme: BIgR antikoerper, IGSF4B antikoerper, NECL1 antikoerper, Necl-1 antikoerper, TSLL1 antikoerper, synCAM3 antikoerper, Igsf4b antikoerper, Necl1 antikoerper, SynCAM3 antikoerper, Tsll1 antikoerper, necl1 antikoerper, cell adhesion molecule 3 antikoerper, cell adhesion molecule 3 S homeolog antikoerper, CADM3 antikoerper, Cadm3 antikoerper, cadm3.S antikoerper

Hintergrund: Cell adhesion molecule 3 (CADM3) is a member of a family of immunoglobulin-like, calcium-independent cell-cell adhesion molecules (1,2). CADM3 localizes to non-junctional contact sites of presynaptic nerve terminals, axons and glia cell processes and is thought to play an important role in the formation of synapses, axon bundles and myelinated axons (3). Recently, CADM3 has been shown to suppress the growth and tumorigenic ability of colon cancer cells, indicating that it can act as a tumor suppressor (4).

Molekulargewicht: Predicted: 44, 48 kDa

Observed: 50 kDa

Gen-ID: 57863

NCBI Accession: NP_067012

UniProt: Q8N126

Pathways: Cell-Cell Junction Organization