KIRREL3 Antikörper (N-Term)

Produktnummer ABIN6992065

Produktdetails anti-KIRREL3 Antikörper

Target: KIRREL3 (Kin of IRRE Like 3 (KIRREL3))

Bindungsspezifität: AA 20-70, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIRREL3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Spezifität: KIRREL3 antibody is human, mouse and rat reactive. At least two isoforms are known to exist, this antibody will detect both isoforms. KIRREL3 antibody is predicted to not cross-react with other members of the KIRREL protein family.

Aufreinigung: KIRREL3 antibody is affinity chromatography purified via peptide column.

Immunogen: KIRREL3 antibody was raised against a 19 amino acid peptide near the amino terminus of human KIRREL3. The immunogen is located within amino acids 20 - 70 of KIRREL3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: KIRREL3 antibody can be used for detection of KIRREL3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: KIRREL3 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: KIRREL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu KIRREL3

Target: KIRREL3 (Kin of IRRE Like 3 (KIRREL3))

Andere Bezeichnung: KIRREL3 (KIRREL3 Produkte)

Synonyme: KIRRE antikoerper, MRD4 antikoerper, NEPH2 antikoerper, PRO4502 antikoerper, 1500010O20Rik antikoerper, 2900036G11Rik antikoerper, SST4 antikoerper, mKIAA1867 antikoerper, kirre like nephrin family adhesion molecule 3 antikoerper, kin of IRRE like 3 (Drosophila) antikoerper, KIRREL3 antikoerper, Kirrel3 antikoerper

Hintergrund: KIRREL3, also known as nephrin-like protein 2, is a type I transmembrane protein belonging to a family of three podocin interacting proteins and the immunoglobulin superfamily (1). KIRREL3 is involved in the regulation of both glomerular and neural development (2), and more specifically, the nucleogenesis of the pontine nuclei in the developing hindbrain (3). KIRREL3 has also been shown to interact with the synaptic scaffold protein calmodulin-associated serine/threonine kinase (CASK) in neuronal cells (4).

Molekulargewicht: Predicted: 64, 84 kDa

Observed: 60 kDa

Gen-ID: 84623

NCBI Accession: NP_115920

UniProt: Q8IZU9