KIRREL2 Antikörper (C-Term)

Produktnummer ABIN6992064

Produktdetails anti-KIRREL2 Antikörper

Target: KIRREL2 (Kin of IRRE Like 2 (Drosophila) (KIRREL2))

Bindungsspezifität: AA 550-600, C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIRREL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Spezifität: KIRREL2 antibody is human, mouse and rat reactive. At least five isoforms are are known to exist. This antibody is predicted to not cross-react with other members of the KIRREL protein family.

Aufreinigung: KIRREL2 antibody is affinity chromatography purified via peptide column.

Immunogen: KIRREL2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human KIRREL2. The immunogen is located within amino acids 550 - 600 of KIRREL2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: KIRREL2 antibody can be used for detection of KIRREL2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: KIRREL2 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: KIRREL2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu KIRREL2

Target: KIRREL2 (Kin of IRRE Like 2 (Drosophila) (KIRREL2))

Andere Bezeichnung: KIRREL2 (KIRREL2 Produkte)

Synonyme: nlg1 antikoerper, neph3 antikoerper, filtrin antikoerper, FILTRIN antikoerper, NEPH3 antikoerper, NLG1 antikoerper, C330019F22Rik antikoerper, cb33 antikoerper, kirrel3 antikoerper, sb:cb33 antikoerper, si:dkey-29g23.1 antikoerper, wu:fb74e02 antikoerper, kirre like nephrin family adhesion molecule 2 antikoerper, kin of IRRE like 2 (Drosophila) antikoerper, kirre like nephrin family adhesion molecule 3, like antikoerper, kirrel2 antikoerper, KIRREL2 antikoerper, Kirrel2 antikoerper, kirrel3l antikoerper

Hintergrund: KIRREL2, also known as nephrin-like 3, is a type I transmembrane protein belonging to the immunoglobulin superfamily of cell adhesion molecules (1). KIRREL2 consists of five extracellular Ig-like repeats, a transmembrane domain, several glycosylation sites and a cytoplasmic domain that has a stretch of nine conserved residues (1,2). KIRREL2 has been found to be expressed in beta cells of pancreatic islets and is involved in the regulation of both glomerular and neural development (3,4). Downregulation of KIRREL2 is implicated in several proteinuric diseases (4,5).

Molekulargewicht: Predicted: 64, 70, 78 kDa

Observed: 70 kDa

Gen-ID: 84063

NCBI Accession: NP_954649

UniProt: Q6UWL6