NINJ1 Antikörper (C-Term)

Produktnummer ABIN6992062

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NINJ1 in WB, ELISA, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für NINJ1 Antikörper (C-Term) (ABIN6992062)

Target: NINJ1 (Ninjurin 1 (NINJ1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NINJ1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-NINJ1 Antikörper

Bindungsspezifität: C-Term

Spezifität: NINJ1 antibody is human, mouse and rat reactive.

Aufreinigung: NINJ1 antibody is affinity chromatography purified via peptide column.

Immunogen: NINJ1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human NINJ1. The immunogen is located within the last 50 amino acids of NINJ1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: NINJ1 antibody can be used for detection of NINJ1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: NINJ1 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: NINJ1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu NINJ1

Target: NINJ1 (Ninjurin 1 (NINJ1))

Andere Bezeichnung: NINJ1

Hintergrund: Ninjurin-1 (NINJ1) is a homophilic adhesion molecule that is strongly induced in dorsal root ganglion (DRG) and Schwann cells following nerve injury and promotes neurite outgrowth of DRG neurons (1,2), suggesting that NINJ1 may play a role in nerve regeneration. NINJ1 is transcriptionally regulated by p53 and is induced by DNA damage in a p53-dependent manner. A deficiency of NINJ1 increases p53 expression, suppresses cell proliferation, but enhances apoptosis and premature senescence in a p53-dependent manner as well as radiation-induced cell mortality (3).

Molekulargewicht: Predicted: 17 kDa

Observed: 16 kDa

Gen-ID: 4814

NCBI Accession: NP_004139

UniProt: Q92982