AKAP4 Antikörper (N-Term)

Produktnummer ABIN6992060

Der Kaninchen Polyklonal Anti-AKAP4-Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, AKAP4 in Proben von Human zu detektieren.

Kurzübersicht für AKAP4 Antikörper (N-Term) (ABIN6992060)

Target: AKAP4 (A Kinase (PRKA) Anchor Protein 4 (AKAP4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKAP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-AKAP4 Antikörper

Bindungsspezifität: N-Term

Spezifität: AKAP4 antibody is human specific. At least three isoforms are known to exist, this antibody will detect the two longest isoforms.

Aufreinigung: AKAP4 antibody is affinity chromatography purified via peptide column.

Immunogen: AKAP4 antibody was raised against a 17 amino acid peptide near the amino terminus of human AKAP4. The immunogen is located within the first 50 amino acids of AKAP4.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: AKAP4 antibody can be used for detection of AKAP4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: AKAP4 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: AKAP4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu AKAP4

Target: AKAP4 (A Kinase (PRKA) Anchor Protein 4 (AKAP4))

Andere Bezeichnung: AKAP4

Hintergrund: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell (1). AKAP4, also known as hAKAP82, is a major sperm fibrous sheath protein that localizes to the entire length of the flagellum of human sperm (2). It has been suggested that AKAP4 plays multiple roles in sperm motility and regulation of signal transduction pathways (2). AKAP4 has also been postulated to be a potential biomarker for breast cancer (3).

Molekulargewicht: Predicted: 94 kDa

Observed: 100 kDa

Gen-ID: 8852

NCBI Accession: NP_003877

UniProt: Q5JQC9