SHBG Antikörper (AA 220-270)

Produktnummer ABIN6992049

Der Kaninchen Polyklonal anti-SHBG Antikörper (ABIN6992049) detektiert spezifisch SHBG in WB, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für SHBG Antikörper (AA 220-270) (ABIN6992049)

Target: SHBG (Sex Hormone Binding Globulin (SHBG))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SHBG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-SHBG Antikörper

Bindungsspezifität: AA 220-270

Spezifität: SHBG antibody is human, mouse, and rat reactive. At least three isoforms of SHBG are known to exist, this antibody will detect all three isoforms.

Aufreinigung: SHBG antibody is affinity chromatography purified via peptide column.

Immunogen: SHBG antibody was raised against a 16 amino acid peptide near the center of human SHBG. The immunogen is located within amino acids 220 - 270 of SHBG.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SHBG antibody can be used for detection of SHBG by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SHBG antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SHBG antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu SHBG

Target: SHBG (Sex Hormone Binding Globulin (SHBG))

Andere Bezeichnung: SHBG

Hintergrund: SHBG is a steroid binding protein that was first described as a plasma protein secreted by the liver and is thought to participate in the regulation of steroid responses. SHBG transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers (1). Low plasma SHBG levels are associated with obesity, abdominal adiposity, metabolic syndrome, and predict the development of type 2 diabetes (2,3). Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus (4).

Molekulargewicht: Predicted: 25, 26, 31, 32, 38, 44 kDa

Observed: 35 kDa

Gen-ID: 6462

NCBI Accession: NP_001031

UniProt: P04278

Pathways: Hormone Transport