BAMBI Antikörper (AA 100-150)

Produktnummer ABIN6992047

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BAMBI in WB, ELISA, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für BAMBI Antikörper (AA 100-150) (ABIN6992047)

Target: BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAMBI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-BAMBI Antikörper

Bindungsspezifität: AA 100-150

Spezifität: BAMBI antibody is human, mouse and rat reactive.

Aufreinigung: BAMBI antibody is affinity chromatography purified via peptide column.

Immunogen: BAMBI antibody was raised against a 17 amino acid peptide near the center of human BAMBI. The immunogen is located within amino acids 100 - 150 of BAMBI.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: BAMBI antibody can be used for detection of BAMBI by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: BAMBI antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: BAMBI antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu BAMBI

Target: BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))

Andere Bezeichnung: BAMBI

Hintergrund: BAMBI (BMP and activin membrane-bound inhibitor homolog, NMA) is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development (1). BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4 (2,3). BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues (4). BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines (5).

Molekulargewicht: Predicted: 29 kDa

Observed: 26 kDa

Gen-ID: 25805

NCBI Accession: NP_036474

UniProt: Q13145