SOX18 Antikörper (N-Term)

Produktnummer ABIN6992041

Produktdetails anti-SOX18 Antikörper

Target: SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))

Bindungsspezifität: AA 40-90, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: SOX18 antibody is human, mouse and rat reactive. SOX18 is predicted to not cross-react with other SOX proteins.

Aufreinigung: SOX18 antibody is affinity chromatography purified via peptide column.

Immunogen: SOX18 antibody was raised against a 17 amino acid peptide near the amino terminus of human SOX18. The immunogen is located within amino acids 40 - 90 of SOX18.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SOX18 antibody can be used for detection of SOX18 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SOX18 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SOX18 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu SOX18

Target: SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))

Andere Bezeichnung: SOX18 (SOX18 Produkte)

Hintergrund: SOX18 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate (1,2). SOX18 is part of the SoxF subgroup which plays an important role in the differentiation of different cell types (3). SOX is known to be involved with vascularization and endothelial development, suggesting that it may be useful as a potential target for inhibiting tumor angiogenesis (4). Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia (5).

Molekulargewicht: Predicted: 42 kDa

Observed: 44 kDa

Gen-ID: 54345

NCBI Accession: NP_060889

UniProt: P35713