HDAC1 Antikörper (C-Term)

Produktnummer ABIN6992034

Dieses Anti-HDAC1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HDAC1 in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für HDAC1 Antikörper (C-Term) (ABIN6992034)

Target: HDAC1 (Histone Deacetylase 1 (HDAC1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HDAC1 Antikörper

Bindungsspezifität: C-Term

Spezifität: HDAC1 antibody is human, mouse and rat reactive. HDAC1 antibody is predicted to not cross-react with other members of the HDAC family.

Aufreinigung: HDAC1 antibody is affinity chromatography purified via peptide column.

Immunogen: HDAC1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human HDAC1. The immunogen is located within the last 50 amino acids of HDAC1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: HDAC1 antibody can be used for detection of HDAC1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: HDAC1 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: HDAC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu HDAC1

Target: HDAC1 (Histone Deacetylase 1 (HDAC1))

Andere Bezeichnung: HDAC1

Hintergrund: The histone deacetylase (HDAC) family contains multiple members which are divided into four classes. Class I of the HDAC family comprises four members, HDAC1, 2, 3, and 8, each of which contains a deacetylase domain and exhibits a different, individual substrate specificity and function in vivo (1). HDAC1 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) (1,2). HDAC1 gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (3,4).

Molekulargewicht: Predicted: 53 kDa

Observed: 54 kDa

Gen-ID: 3065

NCBI Accession: NP_004955

UniProt: Q13547

Pathways: Neurotrophin Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis