PDCL3 Antikörper (C-Term)

Produktnummer ABIN6992031

Der Kaninchen Polyklonal anti-PDCL3 Antikörper (ABIN6992031) detektiert spezifisch PDCL3 in WB, ELISA, IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für PDCL3 Antikörper (C-Term) (ABIN6992031)

Target: PDCL3 (Phosducin-Like 3 (PDCL3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDCL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PDCL3 Antikörper

Bindungsspezifität: C-Term

Spezifität: PDCL3 antibody is human, mouse and rat reactive. PDCL3 antibody is predicted to not cross-react with other members of the PDCL protein family.

Aufreinigung: PDCL3 antibody is affinity chromatography purified via peptide column.

Immunogen: PDCL3 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human PDCL3. The immunogen is located within the last 50 amino acids of PDCL3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PDCL3 antibody can be used for detection of PDCL by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PDCL3 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PDCL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu PDCL3

Target: PDCL3 (Phosducin-Like 3 (PDCL3))

Andere Bezeichnung: PDCL3

Hintergrund: Phosducin-like proteins (PhLPs) are a conserved family of proteins with thioredoxin-like domains that were initially identified as modulators of G protein signaling (1,2). PDCL3 is highly homologous to PDCL and shares an N-terminal helix domain and a C-terminal thioredoxin-fold (Trx-fold) domain (3). Along with the related protein PDCL2, PDCL3 interacts with the chaperonin CCT and modulates CCT-mediated actin and tubulin folding (4). Modulation of PDCL3 levels by MAPK phosphorylation and RhoA-dependent changes also promote cytoskeletal remodeling (5).

Molekulargewicht: Predicted: 26 kDa

Observed: 25 kDa

Gen-ID: 79031

NCBI Accession: NP_076970

UniProt: Q9H2J4