ANGPTL3 Antikörper (C-Term)

Produktnummer ABIN6992023

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ANGPTL3 in WB, ELISA, IF und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für ANGPTL3 Antikörper (C-Term) (ABIN6992023)

Target: ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANGPTL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ANGPTL3 Antikörper

Bindungsspezifität: C-Term

Spezifität: ANGPTL3 antibody is human, mouse and rat reactive. ANGPTL3 antibody is predicted not to cross-react with other ANGPTL family proteins.

Aufreinigung: ANGPTL3 antibody is affinity chromatography purified via peptide column.

Immunogen: ANGPTL3 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human ANGPTL3. The immunogen is located within the last 50 amino acids of ANGPTL3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ANGPTL3 antibody can be used for detection of ANGPTL3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ANGPTL3 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ANGPTL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu ANGPTL3

Target: ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))

Andere Bezeichnung: ANGPTL3

Hintergrund: The angiopoietin-related protein 3 (ANGPTL3) is a member of a family of secreted proteins that function in angiogenesis (1). ANGPTL3 is processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metablism, while the C-terminal chain may be involved in angiogenesis (2,3). Recent experiments have shown that a deficiency of ANGPTL3 is associated with increased insulin sensitivity, lipoprotein lipase activity, and decreased serum free fatty acids, suggesting that ANGPTL3 may also play a role in modulating glucose metabolism (4).

Molekulargewicht: Predicted: 51 kDa

Observed: 53 kDa

Gen-ID: 27329

NCBI Accession: NP_055310

UniProt: Q9Y5C1