ANGPTL3 Antikörper (C-Term)

Produktnummer ABIN6992023

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ANGPTL3 in WB, ELISA, IHC (p) und IF. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für ANGPTL3 Antikörper (C-Term) (ABIN6992023)

Target: ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANGPTL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-ANGPTL3 Antikörper

Bindungsspezifität: C-Term

Spezifität: ANGPTL3 antibody is human, mouse and rat reactive. ANGPTL3 antibody is predicted not to cross-react with other ANGPTL family proteins.

Aufreinigung: ANGPTL3 antibody is affinity chromatography purified via peptide column.

Immunogen: ANGPTL3 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human ANGPTL3. The immunogen is located within the last 50 amino acids of ANGPTL3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ANGPTL3 antibody can be used for detection of ANGPTL3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ANGPTL3 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ANGPTL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu ANGPTL3

Target: ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))

Andere Bezeichnung: ANGPTL3

Hintergrund: The angiopoietin-related protein 3 (ANGPTL3) is a member of a family of secreted proteins that function in angiogenesis (1). ANGPTL3 is processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metablism, while the C-terminal chain may be involved in angiogenesis (2,3). Recent experiments have shown that a deficiency of ANGPTL3 is associated with increased insulin sensitivity, lipoprotein lipase activity, and decreased serum free fatty acids, suggesting that ANGPTL3 may also play a role in modulating glucose metabolism (4).

Molekulargewicht: Predicted: 51 kDa

Observed: 53 kDa

Gen-ID: 27329

NCBI Accession: NP_055310

UniProt: Q9Y5C1