DOCK8 Antikörper (C-Term)

Produktnummer ABIN6992016

Der Kaninchen Polyklonal anti-DOCK8 Antikörper (ABIN6992016) detektiert spezifisch DOCK8 in WB, ELISA und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für DOCK8 Antikörper (C-Term) (ABIN6992016)

Target: DOCK8 (Dedicator of Cytokinesis 8 (DOCK8))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOCK8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-DOCK8 Antikörper

Bindungsspezifität: C-Term

Spezifität: DOCK8 antibody is human, mouse and rat reactive. Multiple isoforms of DOCK8 are known to exist.

Aufreinigung: DOCK8 antibody is affinity chromatography purified via peptide column.

Immunogen: DOCK8 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human DOCK8. The immunogen is located within the last 50 amino acids of DOCK8.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: DOCK8 antibody can be used for detection of DOCK8 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: DOCK8 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: DOCK8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu DOCK8

Target: DOCK8 (Dedicator of Cytokinesis 8 (DOCK8))

Andere Bezeichnung: DOCK8

Hintergrund: The Dedicator of cytokinesis protein 8 (DOCK8) is a member of the DOCK180 family of guanine nucleotide exchange factors (1). DOCK8 plays an essential role in humoral immune responses and is important in the proper formation of the B cell immunological synapse (reviewed in 2). Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome (3).

Molekulargewicht: Predicted: 166, 220, 231 kDa

Observed: 220, 230 kDa

Gen-ID: 81704

NCBI Accession: NP_982272

UniProt: Q8NF50