POU2F3 Antikörper (C-Term)

Produktnummer ABIN6992005

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch POU2F3 in WB, ELISA, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für POU2F3 Antikörper (C-Term) (ABIN6992005)

Target: POU2F3 (POU Class 2 Homeobox 3 (POU2F3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POU2F3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-POU2F3 Antikörper

Bindungsspezifität: AA 370-420, C-Term

Spezifität: POU2F3 antibody is human, mouse and rat reactive. At least two isoforms are known to exist. This antibody will recognize both isoforms. POU2F3 antibody is predicted to not cross-react with other members of the POU domain class 2 family.

Aufreinigung: POU2F3 antibody is affinity chromatography purified via peptide column.

Immunogen: POU2F3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human POU2F3. The immunogen is located within amino acids 370 - 420 of POU2F3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: POU2F3 antibody can be used for detection of POU2F3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: POU2F3 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: POU2F3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu POU2F3

Target: POU2F3 (POU Class 2 Homeobox 3 (POU2F3))

Andere Bezeichnung: POU2F3

Hintergrund: POU2F3, also known as Epoc-1, is a member of a family of POU domain family of transcription factors (1). POU2F3 is expressed primarily in the epidermis and plays a critical role in keratinocyte proliferation and differentiation (1,2). It is a crucial transcription factor that is required for the development of sweet, umami, and bitter, but not sour taste receptor cells (3). POU2F3 is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer (4).

Molekulargewicht: Predicted: 48 kDa

Observed: 55 kDa

Gen-ID: 25833

NCBI Accession: NP_001231611

UniProt: Q9UKI9