FKBP1A Antikörper

Produktnummer ABIN6992004

Der Kaninchen Polyklonal anti-FKBP1A Antikörper (ABIN6992004) detektiert spezifisch FKBP1A in WB, ELISA, ICC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für FKBP1A Antikörper (ABIN6992004)

Target: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FKBP1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-FKBP1A Antikörper

Spezifität: FKBP12 antibody is human, mouse and rat reactive.

Aufreinigung: FKBP12 antibody is affinity chromatography purified via peptide column.

Immunogen: FKBP12 antibody was raised against an 18 amino acid peptide near the center of human FKBP12. The immunogen is located within the first 50 amino acids of FKBP12.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FKBP12 antibody can be used for detection of FKBP12 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: FKBP12 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: FKBP12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu FKBP1A

Target: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Andere Bezeichnung: FKBP12

Hintergrund: FKBP, or FK506 binding protein, is a family of proteins that have prolyl isomerase activity and are related to the cyclophilins in function (1). FKBP12, also called FKBP1, was originally identified as a target of FK506 and rapamycin activity and catalyzes the transition between cis and transproline residues critical for proper folding of proteins (2). FKBP12 is an abundant, evolutionarily conserved cytoplasmic protein that is an important regulator of diverse array of cellular processes including T cell activation, entry into the cell cycle and intracellular calcium release (3-5).

Molekulargewicht: Predicted: 12 kDa

Observed: 12 kDa

Gen-ID: 2280

NCBI Accession: NP_463460

UniProt: P62942

Pathways: Negative Regulation of Transporter Activity, Methionine Biosynthetic Process