IFIT3 Antikörper (C-Term)

Produktnummer ABIN6991994

Produktdetails anti-IFIT3 Antikörper

Target: IFIT3 (Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3))

Bindungsspezifität: AA 380-430, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFIT3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: IFIT3 antibody is human specific. This antibody is predicted to not cross-react with other members of the IFIT protein family.

Aufreinigung: IFIT3 antibody is affinity chromatography purified via peptide column.

Immunogen: IFIT3 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IFIT3. The immunogen is located within amino acids 380 - 430 of IFIT3 .

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IFIT3 antibody can be used for detection of IFIT3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: IFIT3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: IFIT3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu IFIT3

Target: IFIT3 (Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3))

Andere Bezeichnung: IFIT3 (IFIT3 Produkte)

Hintergrund: The interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) protein is a member of a family of tetratricopeptide repeat-containing proteins whose transcription is upregulated by interferons, virus infection, and molecular patterns such as dsRNA or lipopolysaccharides (1,2). These proteins have been suggested to induce anti-viral cellular activities in response to infection (2). IFIT3 has been shown to interact with TBK1 following RNA virus infection, thereby bridging TBK1 to VISA on the mitochondrion and activating IRF3 and thus the immune response (3).

Molekulargewicht: Predicted: 54 kDa

Observed: 50 kDa

Gen-ID: 3437

NCBI Accession: NP_001026853

UniProt: O14879