Density Regulated Protein Antikörper (AA 80-130)

Produktnummer ABIN6991992

Der Kaninchen Polyklonal anti-Density Regulated Protein Antikörper (ABIN6991992) detektiert spezifisch Density Regulated Protein in WB, ELISA, IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Density Regulated Protein Antikörper (AA 80-130) (ABIN6991992)

Target: Density Regulated Protein (DENR) (Density-Regulated Protein (DENR))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Density Regulated Protein Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Density Regulated Protein Antikörper

Bindungsspezifität: AA 80-130

Spezifität: DENR antibody is human, mouse and rat reactive.

Aufreinigung: DENR antibody is affinity chromatography purified via peptide column.

Immunogen: DENR antibody was raised against an 18 amino acid peptide near the center of human DENR. The immunogen is located within amino acids 80 - 130 of DENR.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: DENR antibody can be used for detection of DENR by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: DENR Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: DENR antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu Density Regulated Protein

Target: Density Regulated Protein (DENR) (Density-Regulated Protein (DENR))

Andere Bezeichnung: DEN

Hintergrund: DENR (density-regulated protein), also designated DRP or smooth muscle cell associated protein 3 (SMAP-3), is a 198 amino acid protein that may be involved in the translation of target mRNAs by scanning and recognition of the initiation codon (1). It plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1 (2,3). DENR contains a SUI1 domain and is found in a variety of tissues with highest levels present in skeletal and cardiac muscle. It is up-regulated in ovarian and breast cancer cells by ERBB2 overexpression (4).

Molekulargewicht: Predicted: 22 kDa

Observed: 22 kDa

Gen-ID: 8562

NCBI Accession: NP_003668

UniProt: O43583