SPNS1/Spinster 1 Antikörper (N-Term)

Produktnummer ABIN6991957

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SPNS1/Spinster 1 in WB, ELISA, IF und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SPNS1/Spinster 1 Antikörper (N-Term) (ABIN6991957)

Target: SPNS1/Spinster 1 (SPNS1) (Spinster Homolog 1 (SPNS1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPNS1/Spinster 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SPNS1/Spinster 1 Antikörper

Bindungsspezifität: N-Term

Spezifität: SPINSTER antibody is human specific. At least four isoforms of SPINSTER are known to exist. This antibody is predicted to not cross-react with other members of the spinster family of proteins.

Aufreinigung: SPINSTER antibody is affinity chromatography purified via peptide column.

Immunogen: SPINSTER antibody was raised against an 18 amino acid peptide near the amino terminus of human SPINSTER. The immunogen is located within the first 50 amino acids of SPINSTER.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SPINSTER antibody can be used for detection of SPINSTER by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SPINSTER antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SPINSTER antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu SPNS1/Spinster 1

Target: SPNS1/Spinster 1 (SPNS1) (Spinster Homolog 1 (SPNS1))

Andere Bezeichnung: SPINSTE

Hintergrund: SPINSTER, also known as SPNS1 or SPIN1, is a 528 amino acid multi-pass membrane protein that localizes to the inner mitochondrial membrane and belongs to the spinster subfamily of the major facilitator superfamily (1). SPINSTER interacts with Bcl-x and Bcl-2 and, via this interaction, is thought to be involved in necrotic or autophagic cell death (2). The related protein SPNS2 is critical for the normal lymphocyte localization and mammalian immune system function (1,3).

Molekulargewicht: Predicted: 58 kDa

Observed: 56 kDa

Gen-ID: 83985

NCBI Accession: NP_001135920

UniProt: Q9H2V7