GLIPR1L1 antibody is human specific. At least two isoforms of GLIPR1L1 are known to exist, this antibody will detect both isoforms. This antibody is predicted to not cross-react with other GLIPR or GLIPR-like proteins.
Aufreinigung
GLIPR1L1 antibody is affinity chromatography purified via peptide column.
Immunogen
GLIPR1L1 antibody was raised against an 18 amino acid peptide near the amino terminus of human GLIPR1L1 . The immunogen is located within amino acids 20 - 70 of GLIPR1L1.
GLIPR1L1
Reaktivität: Human
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
FITC
Applikationshinweise
GLIPR1L1 antibody can be used for detection of GLIPR1L1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
GLIPR1L1 antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
GLIPR1L1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target
GLIPR1L1
(GLI Pathogenesis-Related 1 Like 1 (GLIPR1L1))
1700011E04Rik antikoerper, ALKN2972 antikoerper, PRO7434 antikoerper, GLI pathogenesis-related 1 like 1 antikoerper, GLI pathogenesis related 1 like 1 antikoerper, Glipr1l1 antikoerper, GLIPR1L1 antikoerper
Hintergrund
The GLIPR1-like 1 protein (GLIPR1L1) gene is part of a p53 target gene cluster that includes the related proteins GLIPR1 and GLIPR1L2 (1). GLIPR1L1 is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family (2). GLIPR1 is a tumor suppressor whose expression is regulated by p53 (3). Unlike GLIPR1, GLIPR1L1 is expressed primarily in the testis and is thought to be involved in the binding of sperm to the oocyte complex (4).