GLIPR1 Antikörper (AA 60-110)

Produktnummer ABIN6991949

Produktdetails anti-GLIPR1 Antikörper

Target: GLIPR1 (GLI Pathogenesis-Related 1 (GLIPR1))

Bindungsspezifität: AA 60-110

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLIPR1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Spezifität: GLIPR1 antibody is human and mouse reactive. At least two isoforms of GLIPR1 are known to exist, this antibody will detect both isoforms. This antibody is predicted to not cross-react with other GLIPR or GLIPR-like proteins.

Aufreinigung: GLIPR1 antibody is affinity chromatography purified via peptide column.

Immunogen: GLIPR1 antibody was raised against an 18 amino acid peptide near the center of human GLIPR1. The immunogen is located within amino acids 60 - 110 of GLIPR1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: GLIPR1 antibody can be used for detection of GLIPR1 by Western blot at 1 - 2 μ,g/mL. For Immunoflorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: GLIPR1 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: GLIPR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu GLIPR1

Target: GLIPR1 (GLI Pathogenesis-Related 1 (GLIPR1))

Andere Bezeichnung: GLIPR1 (GLIPR1 Produkte)

Synonyme: CRISP7 antikoerper, GLIPR antikoerper, RTVP1 antikoerper, 2410114O14Rik antikoerper, RTVP-1 antikoerper, mRTVP-1 antikoerper, GLIPR1 antikoerper, zgc:65887 antikoerper, GLI pathogenesis related 1 antikoerper, GLI pathogenesis-related 1 antikoerper, GLI pathogenesis-related 1 (glioma) antikoerper, GLI pathogenesis-related 1b antikoerper, GLIPR1 antikoerper, Glipr1 antikoerper, glipr1b antikoerper

Hintergrund: The glioma pathogensis-related protein 1 (GLIPR1) is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family (1). GLIPR1 is a tumor suppressor whose expression is regulated by p53, its increased expression is associated with myelomocytic differentiation in macrophages, whereas decreased expression of this gene through gene methylation is associated with prostate cancer (2). The GLIPR1 gene is part of a p53 target gene cluster that includes GLIPR1L1 and GLIPR1L2, two highly homologous proteins whose expression patterns vary (3).

Molekulargewicht: Predicted: 29 kDa

Observed: 29 kDa

Gen-ID: 11010

NCBI Accession: NP_006842

UniProt: P48060

Pathways: Regulation of Lipid Metabolism by PPARalpha