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GLIPR1 Antikörper (AA 60-110)

Der Kaninchen Polyklonal Anti-GLIPR1-Antikörper wurde für ELISA, WB und IF validiert. Er ist geeignet, GLIPR1 in Proben von Human und Maus zu detektieren.
Produktnummer ABIN6991949

Kurzübersicht für GLIPR1 Antikörper (AA 60-110) (ABIN6991949)

Target

Alle GLIPR1 Antikörper anzeigen
GLIPR1 (GLI Pathogenesis-Related 1 (GLIPR1))

Reaktivität

Human, Maus

Wirt

  • 19
  • 3
  • 1
  • 1
Kaninchen

Klonalität

  • 22
  • 2
Polyklonal

Konjugat

  • 10
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GLIPR1 Antikörper ist unkonjugiert

Applikation

  • 11
  • 9
  • 3
  • 2
  • 1
ELISA, Western Blotting (WB), Immunofluorescence (IF)
  • Bindungsspezifität

    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 60-110

    Spezifität

    GLIPR1 antibody is human and mouse reactive. At least two isoforms of GLIPR1 are known to exist, this antibody will detect both isoforms. This antibody is predicted to not cross-react with other GLIPR or GLIPR-like proteins.

    Aufreinigung

    GLIPR1 antibody is affinity chromatography purified via peptide column.

    Immunogen

    GLIPR1 antibody was raised against an 18 amino acid peptide near the center of human GLIPR1. The immunogen is located within amino acids 60 - 110 of GLIPR1.

    Isotyp

    IgG
  • Applikationshinweise

    GLIPR1 antibody can be used for detection of GLIPR1 by Western blot at 1 - 2 μ,g/mL. For Immunoflorescence start at 5 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    GLIPR1 antibody is supplied in PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,4 °C

    Informationen zur Lagerung

    GLIPR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target

    GLIPR1 (GLI Pathogenesis-Related 1 (GLIPR1))

    Andere Bezeichnung

    GLIPR1

    Hintergrund

    The glioma pathogensis-related protein 1 (GLIPR1) is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family (1). GLIPR1 is a tumor suppressor whose expression is regulated by p53, its increased expression is associated with myelomocytic differentiation in macrophages, whereas decreased expression of this gene through gene methylation is associated with prostate cancer (2). The GLIPR1 gene is part of a p53 target gene cluster that includes GLIPR1L1 and GLIPR1L2, two highly homologous proteins whose expression patterns vary (3).

    Molekulargewicht

    Predicted: 29 kDa

    Observed: 29 kDa

    Gen-ID

    11010

    NCBI Accession

    NP_006842

    UniProt

    P48060

    Pathways

    Regulation of Lipid Metabolism by PPARalpha
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