AQP2 Antikörper (C-Term)

Produktnummer ABIN6991948

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch AQP2 in WB, ELISA, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für AQP2 Antikörper (C-Term) (ABIN6991948)

Target: AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AQP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-AQP2 Antikörper

Bindungsspezifität: C-Term

Spezifität: AQP2 antibody is human, mouse and rat reactive. This antibody is predicted to not cross-react with other members of the aquaporin protein family.

Aufreinigung: AQP2 antibody is affinity chromatography purified via peptide column.

Immunogen: AQP2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AQP2. The immunogen is located within the last 50 amino acids of AQP2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: AQP2 antibody can be used for detection of AQP2 by Western blot at 1 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: AQP2 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: AQP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu AQP2

Target: AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

Andere Bezeichnung: AQP2

Hintergrund: Aquaporins are membrane proteins that serve in the transfer of water and small solutes across cellular membranes. One such aquaporin, aquaporin-2 (AQP2) is located in the kidney collecting tubule and plays a critical role in water reabsorbtion (1). AQP2 is mainly localized in intracellular vesicles but upon stimulation with anti-diuretic hormone (ADH), AQP2 is translocated to the apical plasma membrane by exocytic fusion of AQP2-bearing vesicles (2). Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus (3).

Molekulargewicht: Predicted: 30 kDa

Observed: 28 kDa

Gen-ID: 359

NCBI Accession: NP_000477

UniProt: P41181

Pathways: Response to Water Deprivation